The Micro-Dose Protocol
Micro-dose daily. Ready 24/7 without timing a pill.
B12, K2 and D3 plus a 5 mg micro-dose of tadalafil, in one tablet next to your morning coffee. Ready 24/7, 365. If prescribed by a US-licensed provider.
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You optimize everything else
One tablet next to your morning coffee. Done.
You dial in sleep, training and bloodwork. Then sex comes down to a strong pill and a stopwatch.
This slots in next to your vitamins, and it builds up over about 5 days.
What's inside
Four actives. One daily tablet.
A prescription micro-dose. Blood flow, around the clock.
Energy and nerve health.
Healthy calcium use, with D3.
Bone and immune health.
"Micro-dose" here means 5 mg of tadalafil a day. Compounded medications are not FDA-approved.
What it costs
From $2.12 a day
| Plan | You pay | Per day |
|---|---|---|
| Buy 2, get 1 free | $218today | $2.42 |
| Buy 4, get 2 free | $436today | $2.42 |
| Buy 7, get 5 free | $763today | $2.12 |
| 3-month plan | $89per 28 days | $2.97 |
| Month to month | $109per 25 days | $3.63 |
One tablet is one day, so your price per dose and per day are the same. Charged only if prescribed.
Compare
Micro-dose daily vs. an on-demand pill
| Micro-Dose | On-demand tadalafil | |
|---|---|---|
| Tadalafil per dose | 5 mg | 10–20 mg |
| Plan sex around it | No | Yes |
| Headache, per the prescribing information | Reported less often | Reported more often |
| Added B12, K2, D3 | Yes | No |
Prescribing information for tadalafil: once-daily 2.5–5 mg vs as-needed 10–20 mg, from separate trials. Individual results vary.
The science
Why longevity routines are paying attention
In a long-term study of men, erectile dysfunction was linked to a higher later risk of heart disease, with the biggest jump in younger men.
Inman BA et al. Mayo Clin Proc. 2009;84(2):108–113.
In a small study of 32 men at higher heart risk, tadalafil (20 mg every other day for 4 weeks, a higher dose than this protocol) improved a measure of blood-vessel function.
Rosano GM et al. Eur Urol. 2005;47(2):214–220.
After lab research in mice, small early trials have studied whether tadalafil can help the immune response in some head and neck cancers. This is research only, not a treatment.
Serafini P et al. J Exp Med. 2006;203(12):2691–2702 · Califano JA et al. Clin Cancer Res. 2015;21(1):30–38 · Weed DT et al. Clin Cancer Res. 2015;21(1):39–48.
Research is ongoing and doesn't show that the Micro-Dose Protocol prevents or treats any disease. Vigo MD providers prescribe tadalafil for erectile dysfunction only, not to prevent or treat cancer or heart disease. Individual results vary.
How it works
2 minutes of questions. Zero waiting rooms.
- Check outYour card is held, not charged.
- Answer 2 minutes of health questionsA US-licensed provider reviews them and decides.
- Ships if prescribedCharged and shipped in a plain box. Not prescribed? The hold is released.

Ready on a Tuesday morning. Ready on a Saturday night.
Choose my planFAQ
Questions, answered
Is this a supplement?
What does micro-dose mean?
I'm in my 20s or 30s. Is this for me?
Will I be ready again faster?
Does it prevent cancer or heart disease?
Can I take it with my stack?
How does billing work?
Prepaid plans. Buy 2 get 1, Buy 4 get 2 and Buy 7 get 5 are paid once for 3, 6 or 12 months. Supplies ship every 3 months. When the term ends it renews at the same price until you cancel.
Monthly plans. Month to month bills every 25 days and you can cancel any time. The 3-month plan bills every 28 days with a 3-payment minimum and ships 90 days of supply with the first payment.
Why do I pay before the health questions?
What if I'm not prescribed?
Are compounded medications FDA-approved?
Is this safe with my other medicines?
Can I drink alcohol with it?
What are the side effects?
Is my information private?
How is it shipped?
How do I cancel?
Who shouldn't take this?
Important safety information
Prescription treatment is available only if a US-licensed provider decides it is right for you after reviewing your health questions. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness or quality.
Do not take this treatment if you take nitrates in any form (pills, sprays, patches or ointments), riociguat, or recreational nitrites (poppers); the combination can cause a sudden, dangerous drop in blood pressure. Tell your provider if you have heart problems, low or high blood pressure, liver or kidney problems, or take alpha-blockers.
Get medical help right away for an erection lasting more than 4 hours, chest pain, fainting, or sudden loss of vision or hearing. Common side effects include headache, flushing, a stuffy nose, indigestion, back or muscle aches and dizziness. Individual results vary.
This information does not replace a conversation with your provider.


